Sports News
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| Chicago Fall Tennis Classic | ||
| Surface: Hard | Date: Sep. 27 - Oct. 3 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Maddison Inglis | Win | 5-7, 6-1, 6-0 |
| Third Round | Tereza Martincova | Win | 6-2, 7-6 (7-5) |
| Quarterfinals | Elena Rybakina | Loss | 4-6, 1-3 Retired |
| J&T Banka Ostrava Open 2021 | ||
| Surface: Hard | Date: Sep. 20 - Sep. 26 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Sara Sorribes Tormo | Win | 6-2, 6-3 |
| Quarterfinals | Anett Kontaveit | Loss | 4-6, 3-6 |
| BGL BNP Paribas Luxembourg Open | ||
| Surface: Hard | Date: Sep. 13 - Sep. 19 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Zarina Diyas | Win | 6-1, 6-3 |
| Quarterfinals | Liudmila Samsonova | Loss | 1-6, 4-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 30 - Sep. 12 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Arantxa Rus | Win | 6-4, 6-4 |
| Second Round | Martina Trevisan | Win | 6-3, 6-1 |
| Third Round | Jessica Pegula | Win | 6-2, 6-4 |
| Fourth Round | Iga Swiatek | Win | 7-6 (14-12), 6-3 |
| Quarterfinals | Emma Raducanu | Loss | 3-6, 4-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 15 - Aug. 22 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Marketa Vondrousova | Win | 6-3, 7-5 |
| Second Round | Shelby Rogers | Win | 7-6 (7-1), 6-1 |
| Third Round | Karolina Muchova | Win | 7-5, 2-1 Retired |
| Quarterfinals | Jil Teichmann | Loss | 3-6, 2-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jun. 28 - Jul. 11 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Kaja Juvan | Loss | 3-6, 3-6 |
| Nature Valley International | ||
| Surface: Grass | Date: Jun. 21 - Jun. 26 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Petra Martic | Win | 6-1, 6-3 |
| Second Round | Viktorija Golubic | Loss | 4-6, 4-6 |
| bett1open | ||
| Surface: Grass | Date: Jun. 14 - Jun. 20 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Jule Niemeier | Win | 4-6, 6-4, 7-5 |
| Second Round | Petra Martic | Win | 6-3, 6-4 |
| Quarterfinals | Ekaterina Alexandrova | Win | 6-4, 4-6, 7-6 (7-4) |
| Semifinals | Alize Cornet | Win | 7-5, 6-4 |
| Final | Liudmila Samsonova | Loss | 6-1, 1-6, 3-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 30 - Jun. 13 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Nadia Podoroska | Win | 6-0, 6-3 |
| Second Round | Daria Kasatkina | Loss | 2-6, 2-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 9 - May 16 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Kristina Mladenovic | Loss | 3-6, 4-6 |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 29 - May 9 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Kristina Mladenovic | Win | 6-4, 6-2 |
| Second Round | Bernarda Pera | Win | 3-6, 6-1, 7-6 (7-5) |
| Third Round | Ons Jabeur | Win | 7-6 (7-2), 4-3 Retired |
| Quarterfinals | Paula Badosa | Loss | 4-6, 5-7 |
| Porsche Tennis Grand Prix | ||
| Surface: Clay | Date: Apr. 19 - Apr. 25 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Nastasja Schunk | Win | 6-4, 6-2 |
| Second Round | Ekaterina Alexandrova | Loss | 1-6, 5-7 |
| Volvo Car Open | ||
| Surface: Green Clay | Date: Apr. 5 - Apr. 11 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Paula Badosa | Loss | 2-6, 7-6 (7-2), 1-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 23 - Apr. 4 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Zarina Diyas | Win | 6-2, 6-1 |
| Third Round | Marketa Vondrousova | Loss | 6-4, 4-6, 4-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Mar. 7 - Mar. 13 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Veronika Kudermetova | Win | 6-4, 5-7, 6-4 |
| Third Round | Anastasia Potapova | Loss | 1-6, 6-2, 5-7 |
| Qatar Total Open 2021 | ||
| Surface: Hard | Date: Mar. 1 - Mar. 6 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Madison Keys | Loss | 4-6, 1-6 |
| Adelaide International | ||
| Surface: Hard | Date: Feb. 22 - Feb. 27 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Misaki Doi | Win | 6-1, 6-3 |
| Quarterfinals | Storm Sanders | Win | 6-2, 6-4 |
| Semifinals | Cori Gauff | Win | 7-6 (7-2), 6-7 (4-7), 6-2 |
| Final | Iga Swiatek | Loss | 2-6, 2-6 |
| Australian Open | ||
| Surface: Hard | Date: Feb. 8 - Feb. 21 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Lauren Davis | Win | 6-3, 4-6, 6-1 |
| Second Round | Svetlana Kuznetsova | Win | 7-5, 2-6, 6-4 |
| Third Round | Elise Mertens | Loss | 2-6, 1-6 |
| Grampians Trophy | ||
| Surface: Hard | Date: Feb. 3 - Feb. 7 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Sorana Cirstea | Loss | 5-7, 2-6 |
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